Interceptor® Plus (milbemycin oxime/praziquantel) for Dogs

Interceptor® Plus is a monthly chew that protects dogs and puppies 6 weeks or older and 2 pounds or greater against heartworm disease, adult hookworm, roundworm, tapeworm and whipworm infections.

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Why choose Interceptor® Plus for your dog?

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    Protect your dog against five of the most common types of worms that infect dogs.

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    Single monthly tasty chew for easy administration

  • An icon of Elanco 4 pills

    Available in four different dosing sizes, making it easier to treat dogs of many different sizes with one chew

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    Also treats and controls hookworm, roundworm, whipworm and tapeworms

Complete 5-worm protection starts here

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Prevents: Treats and controls:

Heartworm disease

Hookworm, roundworm, whipworm and tapeworm

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Works for:

Dogs and puppies 6 weeks or older and 2 pounds or greater

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Chewable (real chicken flavor)

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Dosing frequency:


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Requires prescription

Purchasing Interceptor® Plus is easy and convenient

Protects against all 5 major worms, not just 2 or 3

Interceptor® Plus protects your dog against not only heartworm disease, but all five major worms including heartworm, hookworm, roundworm, whipworm and tapeworm. That’s more types of worms than Heartgard® Plus (ivermectin/pyrantel) and Simparica® Trio (sarolaner/moxidectin/pyrantel).

Ask your veterinarian if Interceptor® Plus is the right choice to protect your dog.

Maximum efficacy starts with the right dose of worm protection.

Pill weight chart

Every dog is unique, and yours is no exception. Finding the right dosage is a first step in making sure that your dog's worm protection is effective. Proper administration is also important because it ensures that Interceptor® Plus (milbemycin oxime/praziquantel) can do its job to its fullest ability and keep your dog protected.

For maximum efficacy, your vet will prescribe based on your dog’s weight and may reference the provided dosage/weight chart.

How to administer Interceptor® Plus

1. Remove one tasty chewable from its packaging

Check to make sure that the chewable has not expired, and remove from packaging.

2. Administer chewable

Your dog can take the chewable from your hand or with a small amount of food. Just make sure they consume the whole dose.

3. Check for complete ingestion

After your dog has taken the chewable, observe your pet for a few minutes to ensure that no part of the dose is lost or rejected. If you suspect that any of the dose has been lost, redosing is recommended.

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$15 Interceptor Plus rebate

Enjoy savings on your prescription.

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Register for reminders

Get text or email reminders when it’s time to give your dog each monthly dose, or refill their Interceptor Plus prescription.


Indications for Interceptor Plus

Interceptor Plus prevents heartworm disease and treats and controls adult roundworm, hookworm, whipworm, and tapeworm infections in dogs and puppies 6 weeks or older and 2 pounds or greater.

Important Safety Information

Treatment with fewer than 6 monthly doses after the last exposure to mosquitoes may not provide complete heartworm prevention. Prior to administration of Interceptor Plus, dogs should be tested for existing heartworm infections. The safety of Interceptor Plus has not been evaluated in dogs used for breeding or in lactating females. The following adverse reactions have been reported in dogs after administration of milbemycin oxime or praziquantel: vomiting, diarrhea, decreased activity, incoordination, weight loss, convulsions, weakness, and salivation. For complete safety information, please see Interceptor® Plus product label or ask your veterinarian.

Indications for Credelio

Credelio kills adult fleas and is indicated for the treatment and prevention of flea infestations and treatment and control of tick infestations (lone star tick, American dog tick, black-legged tick and brown dog tick) for one month in dogs and puppies 8 weeks and older and 4.4 pounds or greater.